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Abstract: The field of Nanotechnology has
been revolutionary as substantial technical and
scientific growth in basic sciences plus manipulation by
chemical or physical process of individual atom &
molecules have widened its horizon. In drug therapy we
face the problems of poor solubility, limited chemical
stability, short half life, and poor bioavailability &
strong side effects. The recent development in drug
delivery system has opened up new potential &
possibility for tailor-mare production of pharmaceutical
drugs, oral peptides, gene therapy and
nanocosmeceuticals.
Introduction
The development of effective drug delivery systems that
can transport and deliver a drug precisely and safely to
its site of action is becoming the 'holy grail' of
pharmaceutical researchers. Nanotechnology, the term
derived from Greek word 'nano', meaning dwarf, applies
the principles of engineering, electronics, physical and
material sciences & manufacturing at a molecular and
supra-micron level. The material at nanoscale could be a
device or system or these could be dimension range from
0.1nm-1000 nm. Nanotechnology offer a vision for 'smart'
drug approach involving the design, synthesis &
characterization of material or devices that have
functional association in nanoscale. The idea that
Nanoparticles has unique physical & biological
properties that might be used to overcome the problems
of drug delivery and targeting. This review describes
the use of nano-particulate carrier system as one
solution to overcome delivery problem i.e. nano-sphere,
nano-constructed lipid carrier, solidlipid nanoparticles
(SLN) and the latest innovations in the drug delivery.
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