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THE PHARMA REVIEW FEBRUARY 06
Asymmetric Membrane Capsule : A novel approach for Osmotic Drug Delivery
Kumar Gaurav*, C. S. Chauhan, Sudhir Bhardwaj, P. S. Naruka, G. D. Gupta, R. S. Gaud

Abstract:
Asymmetric membrane capsule are novel non-disintegrating polymeric capsule made by a phase inversion process in which the membrane structure was precipitated on stainless steel mold pins by dipping the mold pins into a coating solution containing a polymer solvent non solvent system followed by dipping into a quench solution. The resulting asymmetric membrane wall was composed of a thin dense region supported on a thicker porous region. The asymmetric membrane capsule can be filled with a blend of the active agent and excipients for use in the active agent and excipients for use in osmotic drug delivery application.

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