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THE PHARMA REVIEW
FEBRUARY 06
Development and Evaluation of
Microparticles of Gugulipid
Y.S.Tanwar, G.D. Gupta and
K.G. Ramawat
Abstract: Hyperlipidemia is a disorder characterized by abnormally high concentrations of lipids in the blood that are correlated with the development of atherosclerosis, the underlying cause of coronary heart disease and stroke. Gugulipid is a standardized extract prepared from the oleo gum resin of Commiphora wightii and has been clinically proven to reduce the levels of harmful serum lipids in the blood stream. Microparticles of gugulipid were formulated by different techniques using chitosan, egg albumin, sodium alginate, ethyl cellulose, cellulose acetate, gelatin and beeswax. The microparticles were evaluated for their physico-chemical characteristics. The HPLC profile showed distinct separation of Guggulsterone-E and-Z; confirming entrapment of gugulipid in the prepared microparticles. The above content is an abstract only. For the full Article please contact: |
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