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THE PHARMA REVIEW JUNE 2006

Pharmacist In Cancer Supportive Care

Vijay Roy, Nishant Kumar, Dr. Puneet Gupta

Abstract: Modern medicine is aging with breath taking advances in cancer care including cancer prevention, detection, therapy, research, rehabilitation and symptom management has seen a sea change over last decade. In India, about 10 lakh new cancer cases are detected every year and about same of old plus new cancer persons die each year. The diagnosis of cancer once confirmed by the doctor does shock the patient beyond such a manner that one is taken aback. The patient and family both suffer differently and that adds to the total burden of cancer related illness. The relationship of a doctor and oncology pharmacist carries with the cancer patient is that of friend, philosopher and guide telling how to add years to life and life to years.

Latest "molecular" targeted therapy has drug categories of two types, the "big molecule" type act on "molecules" outside the cell membrane, as these are not able to penetrate within cancer cell. The second "small molecules" type act on molecules inside the cell. The monoclonal antibodies like anti HER-2, anti CD20, anti EGFR and anti VEGF (Herceptin@, Mabthera@, Erbitux@, Avastin@) respectively belongs to "BIG" type whereas, kinase inhibitors of EGFR, bcr-abl Tyrosine, EGFR (Iressa@, Gleevac@, Tarceva@) are small types.

 

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