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THE PHARMA REVIEW JUNE 2006

Quantum Dots: A Future Drug Delivery System

Kamal Singh Rathore, Rohit Lowalekar, Dr. R. K. Nema, Dr. C. P. Jain

Abstract: Nanotechnology paves new vistas of research in development of novel drug delivery systems and has gained immense hike in past two decades, as it is extremely successful on frontier parameter of targeted drug delivery. Quantum dots are nanoscale semiconductor crystals ranging typically between 1 - 10 nanometer. Quantum dots offer multitude optical and electronic properties that can work around natural limits inherent in traditional semiconductors. Quantum dots are made from tiny bits of metal about thousand times smaller than width of a hair. They can be molded into different shapes and coated with a variety of biomaterials

Quantum dots are used by life-science researchers as tiny beacons or markers, allowing them to see individual genes, nucleic acids, proteins and small molecules especially the new available unique ternary core material with a molecular plate shell. Moreover they are of immense use in the field of disease diagnosis, intracellular tagging, as photosensitizer for treatment of cancer, biotechnology, thermoelectronics, polymer science, bioassays, optical imaging, photovoltaics, optical switching, infrared detectors, chemical sensors, telecommunication components and to develop advanced quantum dot- based anti-counterfeiting materials. Future prospective unfolded by quantum dots are in developing more selective and specific approach of labeling cells and biomolecules and studying their interference effects with normal physiology. It seems that future technology will be based entirely on nanotechnology like quantum dots in all sphere of life.

 

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