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Abstract: The present study was designed
to investigate the analgesic activity of Ammomum
subulatum (Family - Zingiberaceae) fruit extract using
acetic acid induced writhing test and Eddy’s hot plate
method. Ethanolic extract of Ammomum subulatum fruit
showed significant (P < 0.001) reduction in the number
of writhing induced by acetic acid and increased in
reaction time in hot plate test.
Introduction
Ammomum subulatum (Family - Zingiberaceae) is a tall,
perennial plant, with leafy stems, up to 2.5 m in
height, leaves oblong-lanceolate, acuminate, glabrous;
spikes globose, very dense, shortly peduncled;1
Cultivated in swampy places in Bengal, Sikkim, Assam and
Tamil Nadu,2 fruit is large, coarsely striated dark
brown in colour, measuring 2-3 cm in length and upto 1.5
cm in width. It is a trilocular capsule,
anterio-posteriorly flattened, having a number of
irregular, dentate- undulate wings which extend from the
apex downwards for two third of its length. Internally,
the capsule contains several seeds held together by a
viscous pulp of dark brown colour.3 Oil extracted from
the seeds is aromatic, stimulant, stomachic, applied to
eyelids to allay inflammation.4 Decoction of seeds is
used as a gargle in affections of the teeth and gums. In
combination with the seeds of melon it is used as a
diuretic in cases of gravel of the kidneys.5 Seeds are
also used in gonorrhea and as an aphrodisiac. They have
been also found useful in neuralgia in large doses.6
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