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THE PHARMA REVIEW (JANUARY - FEBRUARY 2013)

Taste Assessment in Humans and Rats - A Comparative Approach

Aibani Noorjahan1, Bajaj Amrita & Singh Kavita

Introduction: Oral pharmaceutical products such as orally dissolving tablets, chewable tablets need to reside in the mouth long enough to be tasted hence such formulations should be palatable with good flavor and require taste masking in case of bitter tasting drugs. Such formulations are mainly designed for pediatric and geriatric patient populations. Palatable attributes include appearance, taste, smell, and texture/mouth feel. Taste-masking can provide improved patient compliance, ensuring that medication is taken providing maximum therapeutic benefit and minimum risk of misuse and competitive advantage, particularly for over-the-counter (OTC) products, as consumers will choose the brand that has the least objectionable taste1.

 

 

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