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THE PHARMA REVIEW (JULY AUGUST 2014)

Influence of a Novel Solubilizer Sepitrap-80 on Drug Release from Buccal Tablets of Aceclofenac Using Various Polymers

Dr. Pradnya Palekar Shanbhag, Sneha V. Jog, Manasi M. Chogale1 & Sujata S. Bagal1

Introduction: Among the various routes of drug delivery, the oral route is perhaps the most preferred route for both patients and clinicians alike. However, the various disadvantages associated with per-oral route of drug delivery like hepatic first-pass metabolism and degradation within the GI tract necessitates the investigation of other potential sites of drug administration. 

 

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