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THE PHARMA REVIEW (MARCH APRIL 2014)

Preparation and Evaluation of Oral Disintegrating Tablets of Diclofenac Sodium

B. N. L. Sravanthi, B. Sowjanya, D. Mounica Deepthi Kumari & T. E. G. K. Murthy

Introduction: Over a decade, the demand for development of orally disintegrating tablets (ODTs) has enormously increased as it has significant impact on the patient compliance. Orally disintegrating tablets offer an advantage for populations who have difficulty in swallowing. It has been reported that dysphasia (difficulty in swallowing) is common among all age groups and more specific with pediatric, geriatric population along with institutionalized patients and patients with nausea, vomiting, and motion sickness complications1. Orally disintegrating tablets are also called as or dispersible tablets, quick disintegrating tablets, mouth dissolving tablets, fast disintegrating tablets, fast dissolving tablets, rapid dissolving tablets, porous tablets, and rapimelts. However, of all the above terms, United States pharmacopoeia (USP) approved these dosage forms as orally disintegrating tablets2, 3.

 

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