The Indian drug and pharmaceutical industry is seeing a
rapid advancement in technology, and manufacturing
processes with the transition from process research to
discovering new products. Today, not only has it
achieved global recognition as a “low cost producer of
quality bulk drugs and formulations”; leading Indian
companies have also established marketing and
manufacturing activities in over 60 countries including
USA and Western Europe.
However the more modern the pharmaceutical processes,
the more stringent is the demand for a higher control of
many parameters to ensure a quality final product with
long shelf life. In this article, we will be focusing on
two of the major parameters:
a) Adverse effects of humidity and the most effective
ways to control humidity.
Humidity/moisture is a constant threat to production
efficiency and product quality. Moisture causes problems
like disintegration of tablets, decomposition of
formulations, lumping, caking and agglomeration of
chemical compounds, uneven coating on tablets, inability
to compress tablets, retarded growth in organic cultures
and a shorter shelf life to name just a few.
b) Need to treat fresh air in processing areas to ensure
proper ventilation to maintain IAQ (Indoor Air Quality).
Large quantities of “conditioned” fresh air is needed
for ventilation as well as process needs in many areas
of pharmaceutical production. Since these areas are very
large, conditioning such large volumes of air results in
very high-energy cost. The cost effective solution is to
use equipment to recover substantial part of energy from
exhaust air to keep energy costs down as well as cater
to the fresh air needs.
Thus, control of humidity as well as adequate
conditioned fresh air becomes imperative for the
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