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THE PHARMA REVIEW (MAY 2010)

Edible Vaccines: The New Frontier in Biotechnology

Sarvesh Sharma, R.T. Paliwal, Sukhchain Singh, Vimal Kumar

Abstract
Edible vaccines are like sub-unit vaccines where the selected genes are introduced into the plants and the transgenic plant is then induced to manufacture the encoded protein. Edible vaccines are mucosal targeted vaccines where stimulation of both systematic and mucosal immune network takes place. Foods under study include potatoes, bananas, lettuce, rice, wheat, soybean, corn and legumes. Edible vaccines for various diseases such as measles, cholera, hepatitis-B, and many more are in the process of development. Food vaccines may also help to suppress autoimmunity disorders such as Type-1 Diabetes. Edible vaccine offer exciting possibilities for significantly reducing the burden of diseases like hepatitis & diarrhea in developing world.

 

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