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THE PHARMA REVIEW
(MAY 2010) |
Edible Vaccines: The New
Frontier in Biotechnology
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Sarvesh Sharma, R.T.
Paliwal, Sukhchain Singh, Vimal Kumar |
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Abstract
Edible vaccines are like sub-unit vaccines where the
selected genes are introduced into the plants and the
transgenic plant is then induced to manufacture the
encoded protein. Edible vaccines are mucosal targeted
vaccines where stimulation of both systematic and
mucosal immune network takes place. Foods under study
include potatoes, bananas, lettuce, rice, wheat,
soybean, corn and legumes. Edible vaccines for various
diseases such as measles, cholera, hepatitis-B, and many
more are in the process of development. Food vaccines
may also help to suppress autoimmunity disorders such as
Type-1 Diabetes. Edible vaccine offer exciting
possibilities for significantly reducing the burden of
diseases like hepatitis & diarrhea in developing world.
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