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THE PHARMA REVIEW (MAY JUNE 2019)

Evaluation of Anthelmintic Activity of Delonix Regia

Aminabee SK*, Lakshmana Rao A, Sai Sowmya J, Bhavya Naga Vani V, Teja N & Lakshmi Prasanna P

Introduction: Development of anthelmintic resistance and high cost of conventional anthelmintic drugs lead to evaluation of medicinal plant as an alternative source of anthelminitics. Delonix regia also known as flame of forest, distributed throughout Madagascar,, India, Africa and Australia. The present study was aimed to investigate the anthelmintic activity of crude chloroform extract of the leaves of Delonix regia on Indian earth worm (Pheretima posthuma). Three concentrations (25, 50, 100 mg/ml) of plant extract were studied in anthelmintic activity which involved the estimation of time of paralysis and time of death of the worms. Albendazole in same concentration as that of extract was included as standard reference and normal saline water with 1% CMC as control. The time of paralysis and time of death were studied and activity was compared with the Albendazole suspension as reference standard. The results show that the plant has the potential to be used as anthelmintic.

 

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