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Abstract: Artocarpus lakoocha (Moraceae) is a
widely used medicinal plant by tribals of Jharkhand,
India for the treatment of many diseases. Using DPPH and
Ferric Ion Reducing properties investigated the
antioxidant activity of the plant. The present study
showed that the methanolic extracts from the bark of A.
lakoocha exhibited a strong antioxidant activity. The
flavonoids content was 53.2 mg g-1 and phenolic content
was 0.360 µg/ml. The present study showed that the
Methanolic extracts from the bark of Artocarpus lakoocha
exhibited a strong antioxidant activity, and presence of
Flavonoids and Phenolic content.
Introduction
Phenolic compounds are commonly found in both edible and
nonedible plants, and they have been reported to have
multiple biological effects, including antioxidant
activity. Crude extracts of fruits, herbs, vegetables,
cereals, and other plant materials rich in phenolics are
increasingly of interest in the food industry because
they retard oxidative degradation of lipids and thereby
improve the quality and nutritional value of food. The
importance of the antioxidant constituents of plant
materials in the maintenance of health and protection
from coronary heart disease and cancer is also raising
interest among scientists, food manufacturers, and
consumers as the trend of the future is moving toward
functional food with specific health effects. Free
radical reactions, especially with participation of
oxidative radicals, have been shown to be involved in
many biological processes that cause damage to lipids,
proteins, membranes and nucleic acids, thus giving rise
to a variety of diseases. Reactive oxygen species (ROS)
have been recognized as playing an important role in the
initiation and/or progression of various diseases such
as atherosclerosis, inflammatory injury, and cancer and
cardio vascular disease. Thus, recent studies have
investigated the potential of plant products to serve as
antioxidants against various diseases induced by free
radicals. Additionally, it has been determined that the
antioxidant effect of plant products is mainly due to
phenolic compounds, such as flavonoids, phenolic acids,
tannins and phenolic diterpenes.
Artocarpus lakoocha Roxb. (Hindi: Dahu, Barhal, Beng.
Dahu, Sans. Lokoocha, Eng.: Monkey Jack) is a large
deciduous tree reaching 15-18 m in height with a
spreading head. Reviews of the records in both,
traditional and scientific literature, indicated that
Artocarpus lakoocha Roxb. have many medicinal uses. The
bark in powder form is applied to sores to draw out
purlement matter. The seed and bark of the plant are
reported to be effective in the treatment of stomach and
liver disease. The various compounds have been isolated
from the plant such as cycloartenone, cycloartenol α-
amyrin and leupeol acetate.8 Till date information has
been published on this plant Artocarpus lakoocha.
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