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THE PHARMA REVIEW (NOVEMBER - DECEMBER 2015)

Can Degenerative Diseases be Treated Resulting in Cure?

Dr. S. G. A. Rao

Introduction: Degenerative diseases are diseases remaining after the antibiotic victory over infectious diseases. The other important cause of injury and death is road accidents. The degenerative diseases are the result of cell death. Specialized cells meant to carry out special functions such as muscle or nerve die due to several reasons and are not replaced and this results in loss of function. The loss of function leads to the degenerative disease. A good example would be Parkinsonís disease. This disease is caused by death and degeneration of dopamine secreting neurons in the brain. Loss of dopamine secreting cells results in decreased levels of dopamine. Dopamine is needed for co-ordinated muscle movement. Parkinson patients show a characteristic tremor and inability to move their limbs and body in a coordinated manner. The present way to treat these patients is by giving -Dopa, a precursor of Dopamine through an oral route. This is a very ineffective way of treating this disease and it invariably results in slow and painful death. 

 

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