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THE PHARMA REVIEW (AUGUST - SEPTEMBER 2007)

Application of UV-Spectrophotometric Method for Estimation of
Drotaverine Hydrochloride in Bulk & Tablets

A. A. Shirkhedkar, G. H. Upasani, S.J. Surana

Abstract: A simple, rapid and accurate spectrophotometric method has been developed for the quantitative estimation of Drotaverine HCl (DH) in bulk and tablets. In methanol, DH exhibits absorption at 354 nm and the method obeys Beer's law at the concentration range of 4 - 24 µg/mL. The percentage label claim was found to be in range of 98-101%. The proposed method was validated statistically and by recovery studies.

 
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