BRINGING YOU INFORMATION.  PROVIDING YOU A PLATFORM.

 

 
THE PHARMA REVIEW (SEPTEMBER OCTOBER 2012)

Sodium Alginate Based pH Dependant Delayed Release Coating System for Neutraceuticals - Instanute DR

Chetan Rajsharad, Suresh Pareek & Dario Luini

Introduction:
 
Tablets and capsules are the most frequently used oral dosage forms. The same extends to neutraceutical industry also. Delivery of neutraceuticals encounters same problems as those encountered by active pharmaceutical ingredients i.e. APIs. The principles of gastric protection, enteric coating has now been extended to the neutraceutical industry as well. A large number of neutraceutical products get absorbed from the intestinal area for example absorption of minerals occurs mainly in the duodenum; absorption of water-soluble vitamins, carbohydrates and proteins occurs in the jejunum; and the ileum absorbs fat-soluble vitamins. Hence delivery of neutraceuticals too requires gastric protection so that optimum absorption of nutrition occurs from the absorption window.
Nowadays many vitamin formulations are available in soft gelatin capsule dosage forms. Enteric coating of soft gelatin capsule formulations poses many problems because of the dynamic nature of the capsule shape, such as moisture may permeate into the capsule shell or into the fill liquid during aqueous coating. The drug or filled liquid may migrate into the capsule shell, while the plasticizer or residual water in the gelatin shell may migrate into the fill. These characteristics have to be considered when coating soft gelatin capsules.

 

 

Go to Content Index Page

PHARMA REVIEW - ARTICLES ARCHIVE ( COMPLETE LIST)

 

The above content is an abstract only. For the full Article please contact:
KONGPOSH Publications Pvt. Ltd.
ICS House, C-19, Commercial Complex, SDA, Opp. IIT Gate, New Delhi, India -110016
Tel.: 26855839, 9811195411
Email: kongposhpub@gmail.com, Website: http://www.kppub.com

 
 
 
 

Copyright KONGPOSH PUBLICATIONS Pvt. Ltd.