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THE PHARMA REVIEW (SEPTEMBER OCTOBER 2014)

Fundamentals of Dissolution Test

Sandeep Shah

Introduction: For every pharmaceutical product, it is a must to pass through various testing parameters before it reaches final destination the patient. There are some tests which are called In Process test, which normally covers the testing of physical parameters like Weight, Thickness, Diameter, Hardness, Disintegration, Friability etc.. Some of these tests are also performed again in Quality Control Department, in addition to checking chemical composition. And to do such tests, the first step is to carry out the Dissolution Test. Later followed by checking of absorption through UV Spectrophotometer and / or HPLC depending on specific drug. 

 

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